Evaluation of lauryl chitosan graft polyethyleneimine as a potential carrier of genes and anticancer drugs

► Lauryl chitosan graft polyethyleneimine was synthesised for drug/gene delivery. ► Evaluated its potential to deliver p53 gene and doxorubicin in cancer cell. ► LC-g-PEI showed good blood compatibility, transfection efficiency and drug uptake. ► LC-g-PEI is very attractive gene/drug carrier for further therapeutic applications.