کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10305361 546532 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A voxel-based morphometry study of gray matter correlates of facial emotion recognition in bipolar disorder
ترجمه فارسی عنوان
مطالعه ی مورفومتری مبتنی بر واکسل از ماده ی خاکستری، همبستگی شناخت عاطفه ی صورت در اختلال دوقطبی
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
چکیده انگلیسی
Facial emotion recognition (FER) is one of the many cognitive deficits reported in bipolar disorder (BD) patients. The aim of this study was to investigate neuroanatomical correlates of FER impairments in BD type I (BD-I). Participants comprised 21 euthymic BD-I patients without Axis I DSM IV-TR comorbidities and 21 healthy controls who were assessed using magnetic resonance imaging and the Penn Emotion Recognition Test (ER40). Preprocessing of images used DARTEL (diffeomorphic anatomical registration through exponentiated Lie algebra) for optimized voxel-based morphometry in SPM8. Compared with healthy subjects, BD-I patients performed poorly in on the ER40 and had reduced gray matter volume (GMV) in the left orbitofrontal cortex, superior portion of the temporal pole and insula. In the BD-I group, the statistical maps indicated a direct correlation between FER on the ER40 and right middle cingulate gyrus GMV. Our findings are consistent with the previous studies regarding the overlap of multiple brain networks of social cognition and BD neurobiology, particularly components of the anterior-limbic neural network.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry Research: Neuroimaging - Volume 233, Issue 2, 30 August 2015, Pages 158-164
نویسندگان
, , , , , , , ,