کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10305673 | 546985 | 2015 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Which demographic variables are necessary to correct in neuroimaging studies of serotonin transporter availability? A SPECT study with [123I]ADAM
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
روانپزشکی بیولوژیکی
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چکیده انگلیسی
Previous studies have shown that many demographic variables influence serotonin transporter (SERT) availability as assessed by single photon emission computed tomography (SPECT). The aim of this study was to explore which demographic variables influenced the SERT availability most in a SPECT study with [123I]ADAM. Ninety-five healthy volunteers were recruited. Age, sex, smoking, alcohol intake, educational level, body mass index, seasonal change, and SERT availability were recorded and then analyzed by multivariate linear regression. Age was the only variable that was significantly associated with SERT availability (calculate: (midbrainâcerebellum)/cerebellum). Furthermore, the inverse correlation of age and SERT availability may be present only before the age of 47. Age should be a covariate in SERT-related neuroimaging analyses, particularly in participants under the age of 47 years.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry Research: Neuroimaging - Volume 231, Issue 3, 30 March 2015, Pages 320-324
Journal: Psychiatry Research: Neuroimaging - Volume 231, Issue 3, 30 March 2015, Pages 320-324
نویسندگان
Wei Hung Chang, Lan-Ting Lee, I Hui Lee, Mei Hung Chi, Kao Chin Chen, Nan Tsing Chiu, Wei Jen Yao, Po See Chen, Yen Kuang Yang,