Generalized pixel profiling and comparative segmentation with application to arteriovenous malformation segmentation

► New method for segmenting the inner structure of arteriovenous malformation (AVM). ► Pixel profile function values compared to the current pixel value. ► Linear combination of basic functions generates optimal profile function. ► AVM blood vessels (feeding arteries, draining vein and nidus) delineated in detail. ► Accurate AVM volume calculation.