Histomorphometric analysis of bone tissue from a neolithic skeleton

The histomorphometric analysis of neolithic bone tissue from the radiomorphometricly unaffected 9th thoracic vertebral body of a 20–25 year old man showed significantly elevated bone volume in comparison to the contemporary findings (BV/TV, 28.72% versus 20%). Also the number of trabeculae was clearly higher (Tb.N.: 17.7 cm versus 5.4 cm). The mean width (Tb.Th.) of the plate-shaped trabeculae was 160 μm and 180 μm. Thus, they were significantly wider than current normal findings of 120 μm. These results show a structural, obviously multifactual caused degeneration of spongy bone within the last 6200 years, representing a relatively short period in relation to evolutionary criteria. With regards to the irretrievable loss of preserved bone substance the indication to histomorphometric diagnostic has to be restricted; tissue sampling is only to happen after the carrying-out of all possible non-invasive methods of investigation as well as a comprehensive photo and film documentation. Observing these conditions further fundamental findings for the evolution of bone tissue can be expected through histomorphometry.