A simple approach to prepare monodisperse mesoporous silica nanospheres with adjustable sizes

► A simple approach to obtain monodisperse mesoporous silica nanospheres (MMSNs). ► The particle size can be easily adjusted in the range of 50-110 nm. ► The pore volume and pore size of MMSNs can be enhanced by hydrothermal treatment. ► A spherical micelle templating mechanism proposed to interpret the formation of MMSNs.