کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10392987 | 887125 | 2005 | 28 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The dynamics of single-molecule DNA in flow
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
جریان سیال و فرایندهای انتقال
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The dynamics of single-molecule DNA in flow The dynamics of single-molecule DNA in flow](/preview/png/10392987.png)
چکیده انگلیسی
Within the last decade, fluorescence microscopy of single molecules of DNA in a plethora of flow fields has allowed an unprecedented examination of the dynamics of polymers in flow. As a result, new principles (e.g. “molecular individualism”) have been developed regarding these dynamics and old debates (e.g. conformational hysteresis of polymers in extensional flow) have received a fresh airing. The coupling of the microscopy, employing a spectrum of possible DNA molecules, fragments, and concatemers with dynamic simulation (e.g. Brownian dynamics) has created a tremendous opportunity to both revisit unanswered questions in the field of polymer solution dynamics (particularly in the nonlinear flow regime), as well as to examine new areas surrounding the engineering of flow dynamics of complex fluids in microfluidic devices. The foundation for future studies has been laid by careful experimentation and computer simulation of DNA dynamics in bulk or locally linear flows of many types. Future studies involving collective effects, complex flows, flow-induced reaction, adsorption and so forth are just beginning and again the promise is to develop a new understanding of these polymer processes by examining DNA “one molecule at a time.”
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Non-Newtonian Fluid Mechanics - Volume 130, Issue 1, 10 October 2005, Pages 1-28
Journal: Journal of Non-Newtonian Fluid Mechanics - Volume 130, Issue 1, 10 October 2005, Pages 1-28
نویسندگان
Eric S.G. Shaqfeh,