کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10425141 | 906751 | 2010 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Characterization of calcium phosphate layers grown on polycaprolactone for tissue engineering purposes
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی (عمومی)
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چکیده انگلیسی
Composites fabricated by biomimetic mineral precipitation on polymeric substrates are of interest for tissue engineering. As biological properties of such mineral layers vary with slight changes in composition, a good physical characterization is necessary in order to study their biological activity. In this work polycaprolactone sheets were subjected to air plasma treatment followed by nucleation of calcium phosphate seeds to activate the growth of an apatite-like coating when immersing in simulated body fluid. Two compositions of the SBF were prepared, one of them highly carbonated and the other with no carbonate or magnesium ions. Immersion of PCL in the high carbonate composition produced a low-crystallinity apatite-like layer while the absence of carbonate and magnesium ions yielded a high crystallinity apatite with low Ca/P ratio that is likely partially hydrolyzed octacalciumphosphate (OCP). The morphology, crystal structure and composition of both types of coatings were characterized; osteoblast-like cell adhesion behaviour on different surfaces was observed by fluorescence and electron microscopy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Composites Science and Technology - Volume 70, Issue 13, 15 November 2010, Pages 1796-1804
Journal: Composites Science and Technology - Volume 70, Issue 13, 15 November 2010, Pages 1796-1804
نویسندگان
M. Lebourg, J. Suay Antón, J.L. Gomez Ribelles,