کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10434569 | 910421 | 2005 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Dynamic shear stress in parallel-plate flow chambers
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی پزشکی
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چکیده انگلیسی
An in vitro model using a parallel-plate fluid flow chamber is supposed to simulate in vivo fluid shear stresses on various cell types exposed to dynamic fluid flow in their physiological environment. The metabolic response of cells in vitro is associated with the wall shear stress. However, parallel-plate flow chambers have not been characterized for dynamic fluid flow experiments. We use a dimensionless ratio h/λv, in determining the exact magnitude of the dynamic wall shear stress, with its oscillating components scaled by a shear factor T. It is shown that, in order to expose cells to predictable levels of dynamic fluid shear stress, two conditions have to be met: (1) h/λv<2, where h is the distance between the plates and λv is the viscous penetration depth; and (2) f0
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biomechanics - Volume 38, Issue 1, January 2005, Pages 159-167
Journal: Journal of Biomechanics - Volume 38, Issue 1, January 2005, Pages 159-167
نویسندگان
Rommel G. Bacabac, Theo H. Smit, Stephen C. Cowin, Jack J.W.A. Van Loon, Frans T.M. Nieuwstadt, Rob Heethaar, Jenneke Klein-Nulend,