کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10435668 911010 2016 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Non-viral magnetic engineering of endothelial cells with microRNA and plasmid-DNA-An optimized targeting approach
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
پیش نمایش صفحه اول مقاله
Non-viral magnetic engineering of endothelial cells with microRNA and plasmid-DNA-An optimized targeting approach
چکیده انگلیسی
We show that polyethyleneimine/magnetic nanoparticles based delivery vector (PEI/MNP) is suitable for production of miRNA-modified endothelial cells in terms of efficiency and safety. The obtained transfected cells can be guided to the site of interest using a magnetic field and their fate can be noninvasively traced using magnetic resonance imaging. This multifunctional approach for transient cell modification bears particular interest as a basis for clinically relevant cell engineering.114
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nanomedicine: Nanotechnology, Biology and Medicine - Volume 12, Issue 8, November 2016, Pages 2353-2364
نویسندگان
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