Polyhydroxylated fullerenols regulate macrophage for cancer adoptive immunotherapy and greatly inhibit the tumor metastasis

Adoptive immunotherapy is one of the efficacious methods in carcinoma treatment. Polyhydroxylated fullerenols could regulate macrophage and contribute to the cancer immunotherapy. Activated macrophages inhibit the growth and metastasis of various cancer cells, which is attributed to the multi-cytokines release via the NF-¦ÊB signaling.171