3D electrospun silk fibroin nanofibers for fabrication of artificial skin

2D nanofibers produced using the traditional electrospinning technique play an important role in a variety of applications. Nevertheless, a full-thickness, large-pore 3D nanofiber scaffold is strongly desired for use as biomaterial in tissue engineering. In this work, we have successfully introduced a new technique that can produce 3D nanofiber scaffolds with high porosity and, most importantly, with full thickness for tissue regeneration using cold-plate electrospinning.277