Recognition of multiepitope dendrimeric antigens by human immunoglobulin E

Multivalent biepitope dendrimeric antigens (DeAns) carrying benzylpenicilloyl and amoxicilloyl determinants reveal chemical composition and spatial rearrangement as crucial factors for the patient antibody (IgE)-antigen recognition process. The precise structure of the studied DeAns allows rationally-designed in vitro studies and the possibility of improved clinical assays.69