کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10435871 911017 2016 37 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Transferrin-modified liposome promotes α-mangostin to penetrate the blood-brain barrier
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
پیش نمایش صفحه اول مقاله
Transferrin-modified liposome promotes α-mangostin to penetrate the blood-brain barrier
چکیده انگلیسی
Representative schematic of α-M liposome modified with transferrin for brain targeting. First, the α-M liposome was modified with transferrin to prepare the Tf(α-M) liposome. After investigation of the intracellular liposome distribution and transport across the BBB in vitro, the liposome was injected into the rats via the tail vein. The Tf(α-M) liposome was transported across the BBB via the receptor-mediated endocytosis pathway. Finally, the improvement of brain delivery of α-M was measured.119
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nanomedicine: Nanotechnology, Biology and Medicine - Volume 12, Issue 2, February 2016, Pages 421-430
نویسندگان
, , , , , , , ,