Efficient delivery of immunostimulatory DNA to mouse and human immune cells through the construction of polypod-like structured DNA

A graphical image representing the correlation between the pod number of CpG polypodna (top, light blue) and the cellular uptake and cytokine release from immune cells, including human PBMC (bottom, pale red): increasing the pod number increases the cellular uptake of polypodna and cytokine release.148