Photoinduced electron-transfer mechanisms for radical-enhanced photodynamic therapy mediated by water-soluble decacationic C70 and C84O2 Fullerene Derivatives

Decationically-armed C70 or C84(O2) fullerenes can be excited by UVA, blue, green, white or red light to produce varying amounts of hydroxyl radicals (electron transfer) or singlet oxygen (energy transfer) that can kill cancer cells. Ascorbic acid can potentiate electron transfer but quench singlet oxygen.68