کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10436242 911050 2011 17 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nanomedicine approaches in vascular disease: a review
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
پیش نمایش صفحه اول مقاله
Nanomedicine approaches in vascular disease: a review
چکیده انگلیسی
Vascular diseases are the major causes of morbidity and mortality globally. Current vascular therapeutic strategies involving direct systemic administration of drugs suffer from sub-optimal performance due to rapid drug clearance, lack of site-specific action and low therapeutic index, often resulting in severe systemic side effects like coagulopathy and hemorrhage. Targeted nanomedicine approaches involving vascular site-selective drug delivery and controlled release using bioengineered nanoconstructs, utilizing disease-specific molecular and cellular mechanisms, can revolutionize vascular therapeutics. In addition, such approaches can refine diagnostic imaging of vascular diseases. This article aims to provide a comprehensive review of the promising vascular nanomedicine approaches.141
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nanomedicine: Nanotechnology, Biology and Medicine - Volume 7, Issue 6, December 2011, Pages 763-779
نویسندگان
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