Cognitive behavioural treatment for chronic fatigue syndrome in a rehabilitation setting: Effectiveness and predictors of outcome

► We studied CBT with GET for CFS in the daily practice of a tertiary rehabilitation centre. ► It concerns an uncontrolled implementation study of an inpatient group therapy. ► Large effect sizes were found on fatigue and physical impairment. ► Clinically significant improvement was found in 34% of the patients at post-treatment and 31% at follow-up. ► CBT with GET for CFS is not only effective in RCT's but also in daily practice.