کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10461800 924564 2013 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Update: Studies of prepulse inhibition of startle, with particular relevance to the pathophysiology or treatment of Tourette Syndrome
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Update: Studies of prepulse inhibition of startle, with particular relevance to the pathophysiology or treatment of Tourette Syndrome
چکیده انگلیسی
► We review the cross-species utility of prepulse inhibtion (PPI) as an operational measure of sensorimotor gating. ► PPI deficits in Tourette Syndrome (TS) and in other neurodevelopmental brain disorders are discussed. ► The neurobiological regulation of PPI by forebrain circuitry implicated in the pathophysiology of TS is described. ► A conceptual linkage is noted between deficient sensorimotor gating and intrusive sensory phenomena now recognized as a core feature of TS. ► An update of recent findings relevant to the relationship of PPI to TS is provided.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience & Biobehavioral Reviews - Volume 37, Issue 6, July 2013, Pages 1150-1156
نویسندگان
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