کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10463159 925105 2013 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Assessing the mechanism of response in the retrosplenial cortex of good and poor navigators
ترجمه فارسی عنوان
ارزیابی مکانیزم پاسخ در قشر دلفریب از ناوبرهای خوب و فقیر
کلمات کلیدی
قشر انتروسپلنیال، پایداری، نشانه ها، جهت یابی، حافظه اپیزودیک،
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی
The retrosplenial cortex (RSC) is consistently engaged by a range of tasks that examine episodic memory, imagining the future, spatial navigation, and scene processing. Despite this, an account of its exact contribution to these cognitive functions remains elusive. Here, using functional MRI (fMRI) and multi-voxel pattern analysis (MVPA) we found that the RSC coded for the specific number of permanent outdoor items that were in view, that is, items which are fixed and never change their location. Moreover, this effect was selective, and was not apparent for other item features such as size and visual salience. This detailed detection of the number of permanent items in view was echoed in the parahippocampal cortex (PHC), although the two brain structures diverged when participants were divided into good and poor navigators. There was no difference in the responsivity of the PHC between the two groups, while significantly better decoding of the number of permanent items in view was possible from patterns of activity in the RSC of good compared to poor navigators. Within good navigators, the RSC also facilitated significantly better prediction of item permanence than the PHC. Overall, these findings suggest that the RSC in particular is concerned with coding the presence of every permanent item that is in view. This mechanism may represent a key building block for spatial and scene representations that are central to episodic memories and imagining the future, and could also be a prerequisite for successful navigation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cortex - Volume 49, Issue 10, November–December 2013, Pages 2904-2913
نویسندگان
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