Hemispheric asymmetry in interpreting novel literal language: An event-related potential study

► Recorded ERPs to sentence final words presented in each visual hemifield. ► Predictability modulated the late frontal positivity in rvf/LH only. ► Semantic novelty modulated the late frontal positivity in lvf/RH only. ► Data suggest a role for left frontal cortex in predictive language processing. ► Right frontal cortex implicated in the comprehension of novel literal language.