Acute effects of nicotine administration during prospective memory, an event related fMRI study

► Behaviourally, acute nicotine administration facilitates prospective memory (PM). ► Event-related fMRI more naturalistically evokes PM. ► PM increased lateral prefrontal (BA10) and decreased medial prefrontal activity. ► PM additionally recruited bilateral parietal activity. ► Acute nicotine administration reduced right parietal activity during PM task.