کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10466286 925759 2009 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Impaired control of the oculomotor reflexes in Parkinson's disease
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Impaired control of the oculomotor reflexes in Parkinson's disease
چکیده انگلیسی
To investigate the role of the basal ganglia in integrating voluntary and reflexive behaviour, the current study examined the ability of patients with Parkinson's disease to voluntarily control oculomotor reflexes. We measured the size of the fixation offset effect (the reduction in saccadic reaction time when a fixation point is removed) during a block of pro- and a block of anti-saccades. Healthy controls showed the expected reduction of the FOE during the anti-saccades, which results from efforts to suppress reflexive eye movements (a preparatory set characterized by increased internal control and reduced external control). However, there was no reduction of the FOE in the anti-saccade task in Parkinson's patients, indicating that they are impaired in exerting control over oculomotor reflexes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuropsychologia - Volume 47, Issue 13, November 2009, Pages 2909-2915
نویسندگان
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