کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10466351 | 925760 | 2010 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Altered connectivity between prefrontal and sensorimotor cortex in conversion paralysis
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Altered connectivity between prefrontal and sensorimotor cortex in conversion paralysis Altered connectivity between prefrontal and sensorimotor cortex in conversion paralysis](/preview/png/10466351.png)
چکیده انگلیسی
In the current study, we investigated changes in the inter-regional coupling between prefrontal cortex (PFC) and sensorimotor regions when CP patients imagined movements involving either the affected or the unaffected hand. We found that there were distinct connectivity patterns for different parts of the PFC. While ventromedial PFC was not functionally connected to the motor system, we observed strong functional coupling between the dorsolateral PFC and various sensorimotor areas. Furthermore, this coupling was modulated by whether patients imagined movements of their affected or unaffected hand. Together, these results suggest that the reduced motor responsitivity observed in CP may be linked to altered dorsolateral prefrontal-motor connectivity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuropsychologia - Volume 48, Issue 6, May 2010, Pages 1782-1788
Journal: Neuropsychologia - Volume 48, Issue 6, May 2010, Pages 1782-1788
نویسندگان
Floris P. de Lange, Ivan Toni, Karin Roelofs,