کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1048916 | 945511 | 2007 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Efficacy calculation in randomized trials: Global or local measures?
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
سیاست های بهداشت و سلامت عمومی
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چکیده انگلیسی
This study tests whether the effect of a vaccine trial varies in space and why. Analytical z-score maps identify unusually high- and low-efficacy values in a trial area. Relationships between neighborhood efficacy and ecological variables are measured to explain why efficacy varies in space. Efficacy was found to vary regardless of neighborhood size and the variation is related to several ecological determinants. Local efficacy measures can help public health practitioners make better decisions about when and where to vaccinate populations. The concepts offered in this study are pertinent for any health intervention trial, not just vaccines.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Health & Place - Volume 13, Issue 1, March 2007, Pages 238–248
Journal: Health & Place - Volume 13, Issue 1, March 2007, Pages 238–248
نویسندگان
Michael Emch, Mohammad Ali, Camilo Acosta, Mohammad Yunus, David A. Sack, John D. Clemens,