Neighborhood deprivation and clinical outcomes among head and neck cancer patients

► Neighborhood economic deprivation may have a unique effect on cancer outcomes. ► We examine this among head and neck cancer patients from a large treatment center. ► Neighborhood deprivation predicted poorer survival among oropharyngeal patients. ► It also predicted more secondary malignancies among oropharyngeal patients. ► Oropharyngeal cancer patients from deprived areas may need additional interventions.