Hepatoprotective effect of 2,3-dehydrosilybin on carbon tetrachloride-induced liver injury in rats

► DHS markedly reduced serum AST and ALT levels in CCl4-treated rats. ► DHS inhibits the lipid peroxidation and DNA damage in CCl4-treated rats. ► DHS increases the activity of antioxidant enzymes in CCl4-treated rats. ► DHS attenuates CCl4-induced inflammatory mediators in CCl4-treated rats.