High-efficient column chromatographic extraction of curcumin from Curcuma longa

► Curcumin is one of the important food additive and a potential therapeutic agent. ► High-efficient and low-cost column chromatographic extraction methods developed. ► More than 99% extraction rate with 8-fold 80% ethanol for quantitative analysis. ► More than 99% extraction rate with 2-fold 80% ethanol for large production. ► High content extracts, minimum use of solvent and minimum energy costs.