Chemical composition and antimicrobial activity of the essential oil of Lippia grandis Schauer (Verbenaceae) from the western Amazon

► Brazilian culinary uses the specie Lippia grandis Schauer as a kind of spice. ► The chemical composition of the essential oil of L. grandis was determined. ► The carvacrol (37.12%), ρ-cymene (11.64%), and thymol (7.83%) as the main components. ► The agar disk diffusion method of the essential oil was effective against Staphylococcus aureus, Enterococcus faecalis, and Escherichia coli. ► The minimum inhibitory concentration was 0.57 mg/mL for E. faecalis and 1.15 mg/mL for all the other strains.