Protective effect of arabinose and sugar beet pulp against high glucose-induced oxidative stress in LLC-PK1 cells

► l-Arabinose and SBP inhibited high glucose-induced cytotoxicity and lipid peroxidation, and they elevated glucose uptake. ► They also down-regulated the expressions of iNOS, COX-2 and NF-κB induced by 45 mM glucose in LLC-PK1 cells. ► Arabinose exhibited stronger inhibitory activity on high glucose-induced oxidative stress than SBP did. ► l-Arabinose and SBP are promising antioxidative agents with protective activities against hyperglycemia.