Improved determination of 2-dodecylcyclobutanone in irradiated ground beef patties by gas-chromatography-mass-spectrometry (GC/MS) coupled with solid-phase microextraction (SPME) technique

► 2-Dodecylcyclobutanone (DCB) as irradiation marker. ► Optimised extraction from ground beef patties by SPME and GC/MS analysis. ► Lower limit of quantification of 5 ppb. ► Linear dose-response relationship in the range of 0.5-8 kGy.