An analytical approach to profile steroidal saponins in food supplements: The case of Ruscus aculeatus

► Ruscus aculeatus food supplements in prevention of microcirculation diseases. ► Active steroidal saponins in R. aculeatus commercial products. ► Rapid analysis of R. aculeatus saponins by HPLC-ESI/ITMS2. ► Six furostanol saponins never reported before.