Quantitative determination of wine polysaccharides by gas chromatography-mass spectrometry (GC-MS) and size exclusion chromatography (SEC)

► This study evaluates the suitability of GC-MS for determining the content of wine polysaccharides. ► Good values of LOD, LOQ, repeatability, reproducibility and overall recoveries are achieved. ► GC-MS is more sensitive than FID and provides unambiguous quantification of wine monosaccharides. ► HRSEC-RID could be a rapid and simple method to estimate the content of wine polysaccharides. ► HRSEC-RID cannot be used to quantify specific polysaccharide families.