Anticholinesterase and antioxidant effects of the ethanol extract, ethanol fractions and isolated flavonoids from Cistus laurifolius L. leaves

► The ethanol extract Cistus laurifolius caused remarkable acetylcholinesterase inhibition. ► The n-butanol and ethyl acetate fractions showed potent antioxidant activity. ► Total phenol and flavonoid contents were well-correlated with antioxidant activity. ► Three isolated flavonoid derivatives were also tested in the same manner. ► 3,7-O-dimethylkaempferol (3) was found to be the most potent in antioxidant activity assays.