Mumefural and related HMF derivatives from Japanese apricot fruit juice concentrate show multiple inhibitory effects on pandemic influenza A (H1N1) virus

► Five compounds were isolated from fruit-juice concentrate of Japanese apricot. ► Four HMF derivatives, but not HMF, exhibited lectin-like activity. ► Mumefural and its derivative can abolish hemagglutination of influenza virus. ► Mumefural was the most active anti-sialidase compound of all five isolated compounds. ► Mumefural inhibited the growth of a novel pandemic 2009 H1N1 virus in cell culture.