Cellular assessment of the extract of bambangan (Mangifera pajang) as a potential cytoprotective agent for the human hepatocellular HepG2 cell line

► Quercetin and M. pajang kernel extract showed cytoprotective action in HepG2 cells. ► Expression of NQO1, GR and MSRA was up-regulated by quercetin. ► NQO1, GR and MSRA appear to play a role in the action of quercetin. ► Expression of GR and MSRA was up-regulated by the kernel extract. ► GR and MSRA appear to play a role in the action of bambangan kernel extract.