Factors affecting lipase digestibility of emulsified lipids using an in vitro digestion model: Proposal for a standardised pH-stat method

► Lipid digestion depends on oildroplet characteristics. ► Lipid digestion depends on simulated intestinal fluid composition. Digestion rate increases with decreasing droplet concentration and size. ► Digestion rate increases with decreasing bile, and increasing lipase and calcium. ► A standardised pH-stat titration method is proposed to model lipid digestion.