Multiresidue HPLC method to measure benzimidazole anthelmintics in plasma and egg from laying hens. Evaluation of albendazole metabolites residue profiles

► The validation of a HPLC method to quantify 10 benzimidazole drugs is reported. ► The validation was performed in plasma and egg from laying hens. ► The plasma pharmacokinetic behaviour of albendazole was studied in hen. ► Albendazole and its sulphoxide and sulphone metabolites were measured in plasma. ► Residual egg concentrations of albendazole metabolites were detected.