کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10588725 | 981485 | 2011 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antiproliferative and apoptotic sesquiterpene lactones from Carpesium faberi
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Antiproliferative and apoptotic sesquiterpene lactones from Carpesium faberi Antiproliferative and apoptotic sesquiterpene lactones from Carpesium faberi](/preview/png/10588725.png)
چکیده انگلیسی
Four new (1-4) and 13 known sesquiterpene lactones together with two known diterpenes were isolated from Carpesium faberi. All isolated compounds were evaluated for their antiproliferative activities against MCF-7 human breast cancer cells using the MTT assay. The sesquiterpene lactones (except tomentosin 17) possessing an α-methylene-γ-lactone moiety were found to have significant antiproliferative activities. The cell cycle-specific inhibition and apoptosis induced by selected compounds were investigated using flow cytometry (FCM).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 21, Issue 1, 1 January 2011, Pages 366-372
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 21, Issue 1, 1 January 2011, Pages 366-372
نویسندگان
Xu-Wen Li, Liang Weng, Xue Gao, Yun Zhao, Fei Pang, Jian-Hui Liu, Hong-Feng Zhang, Jin-Feng Hu,