Structure activity optimization of 6H-pyrrolo[2,3-e][1,2,4]triazolo[4,3-a]pyrazines as Jak1 kinase inhibitors

Structure activity optimization of 6H-pyrrolo[2,3-e][1,2,4]triazolo[4,3-a]pyrazines as Jak1 kinase inhibitors

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 25, Issue 20, 15 October 2015, Pages 4399-4404

Michael Friedman, Kristine E. Frank, Ana Aguirre, Maria A. Argiriadi, Heather Davis, Jeremy J. Edmunds, Dawn M. George, Jonathan S. George, Eric Goedken, Bryan Fiamengo, Deborah Hyland, Bin Li, Anwar Murtaza, Michael Morytko, Gagandeep Somal,