Design, synthesis and evaluation of MCH receptor 1 antagonists-Part II: Optimization of pyridazines toward reduced phospholipidosis and hERG inhibition

Design, synthesis and evaluation of MCH receptor 1 antagonists-Part II: Optimization of pyridazines toward reduced phospholipidosis and hERG inhibition

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 25, Issue 16, 15 August 2015, Pages 3270-3274

Gerald J. Roth, Armin Heckel, Jörg T. Kley, Thorsten Lehmann, Stephan G. Müller, Thorsten Oost, Klaus Rudolf, Kirsten Arndt, Ralph Budzinski, Martin Lenter, Ralf R.H. Lotz, Marcus Schindler, Leo Thomas, Dirk Stenkamp,