کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10591827 | 981767 | 2014 | 16 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis of novel β-carboline based chalcones with high cytotoxic activity against breast cancer cells
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis of novel β-carboline based chalcones with high cytotoxic activity against breast cancer cells Synthesis of novel β-carboline based chalcones with high cytotoxic activity against breast cancer cells](/preview/png/10591827.png)
چکیده انگلیسی
A novel series of β-carboline based chalcones was synthesized and evaluated for their cytotoxic activity against a panel of human cancer cell lines. Among all, compound 7c was identified as the most potent analogue that showed marked apoptotic activity in breast cancer cells.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 24, Issue 13, 1 July 2014, Pages 2820-2824
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 24, Issue 13, 1 July 2014, Pages 2820-2824
نویسندگان
Shikha S. Chauhan, Anup K. Singh, Sanjeev Meena, Minaxi Lohani, Akhilesh Singh, Rakesh K. Arya, Srikanth H. Cheruvu, Jayanta Sarkar, Jiaur R. Gayen, Dipak Datta, Prem M.S. Chauhan,