کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10592742 981798 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Rationally designed hybrid molecules with appreciable COX-2 inhibitory and anti-nociceptive activities
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Rationally designed hybrid molecules with appreciable COX-2 inhibitory and anti-nociceptive activities
چکیده انگلیسی
Six molecules were obtained by the combination of three biologically and medicinally significant moieties-indole, chrysin and pyrazole. Bio-evaluation of these hybrid molecules showed significant inhibition of COX-2 enzymatic activity over that of COX-1 and appreciable anti-nociceptive activity, checked at swiss albino mice.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 24, Issue 1, 1 January 2014, Pages 77-82
نویسندگان
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