Development of 99mTc(CO)3-dendrimer-FITC for cancer imaging

Scintigraphy image of normal (a) and melanoma-bearing mice (b) injected with 99mTc(CO)3-dendrimer-FITC, 1 h post-injection. (a) White and yellow arrows point liver and kidneys respectively. (b) White bracket shows the region where the tumor was located. Yellow bracket shows the abdominal region (liver and kidneys) where mask was placed in order to avoid image interference with tumor region. Low uptake observed in surrounding muscle tissues provides good contrast for tumor imaging.