A regio- and stereoselective 1,3-dipolar cycloaddition for the synthesis of new-fangled dispiropyrrolothiazoles as antimycobacterial agents

Dispiropyrrolidine analogues were synthesized and tested for their in vitro antimycobacterial activity. Compounds 5f showed an interesting activity against a strain of Mycobacterium tuberculosis H37Rv and INHR M. tuberculosis.