Synthesis of 3-(1-alkyl/aminoalkyl-3-vinyl-piperidin-4-yl)-1-(quinolin-4-yl)-propan-1-ones and their 2-methylene derivatives as potential spermicidal and microbicidal agents

Biological activity: Tartarate salt of 3-(1-pentyl-3-vinyl-piperidin-4-yl)-1-quinolin-4-yl-propan-1-one (27) was found to be more active spermicidal agent than nonoxynol-9.