Synthesis and evaluation of 8-amino-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives as glycogen synthase kinase-3 (GSK-3) inhibitors

8-Amino-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives as novel glycogen synthase kinase-3 (GSK-3) inhibitors were reported.