Synthesis and biological evaluation of trans 6-methoxy-1,1-dimethyl-2-phenyl-3-aryl-2,3-dihydro-1H-inden-4-yloxyalkylamine derivatives against drug susceptible, non-replicating M. tuberculosis H37Rv and clinical multidrug resistant strains

Compound 1i exhibited 1.35 log10 reduction of the CFU in the lungs and was active against non-replicating M. tb under anaerobic condition.