A rate determining step change in the pre-steady state of acetylcholinesterase inhibitions by 1,n-alkane-di-N-butylcarbamates

A discontinuity of the pre-steady state −log Ks, values for the acetylcholinesterase inhibitions by tether inhibitors 8-14 versus the tether lengths plot, concave downwards, is indicative of a rate determining change in the Ks step.