کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10599063 982047 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A convenient one-pot synthesis of asymmetric 1,3,5-triazine-2,4,6-triones and its application towards a novel class of gonadotropin-releasing hormone receptor antagonists
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
A convenient one-pot synthesis of asymmetric 1,3,5-triazine-2,4,6-triones and its application towards a novel class of gonadotropin-releasing hormone receptor antagonists
چکیده انگلیسی
A convenient one-pot synthetic route was developed for the preparation of asymmetric 1,3-dialkyl-1,3,5-triazine-2,4,6-triones from isocyanates, primary amines and N-chlorocarbonyl isocyanate. This methodology was applied to the synthesis of a chemical library acting as antagonists of the hGnRH receptor.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 15, Issue 3, 1 February 2005, Pages 693-698
نویسندگان
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